Small cell lung cancer (SCLC) is a fast-growing and aggressive form of lung cancer. While it accounts for about 10–15% of all lung cancer cases, it often spreads quickly and can become life-threatening if not caught early. Unfortunately, the disease often progresses silently, with symptoms appearing only after it has already advanced.
Knowing the risks and signs of SCLC — and seeking medical help promptly — can play a critical role in getting treatment early and improving outcomes.
🔍 What Is Small Cell Lung Cancer?
SCLC starts in the lung’s central airways and grows rapidly. It is named for the small size of the cancer cells when viewed under a microscope. Compared to non-small cell lung cancer (NSCLC), SCLC is more aggressive and more likely to spread to other organs such as the liver, bones, and brain.
There are two stages:
• Limited stage: Cancer is in one lung and possibly nearby lymph nodes.
• Extensive stage: Cancer has spread to the other lung, distant lymph nodes, or other parts of the body.
⚠️ Symptoms of Small Cell Lung Cancer
In its early stages, SCLC may not cause any obvious symptoms. As the cancer grows, you might experience:
• Persistent cough
• Shortness of breath
• Chest pain or tightness
• Fatigue or weakness
• Unexplained weight loss
• Wheezing
• Hoarseness
• Swelling in the face or neck
• Frequent lung infections (like bronchitis or pneumonia)
Some symptoms, such as facial swelling or dizziness, may indicate that the cancer is pressing on major blood vessels — a sign of advanced disease.
🧬 Risk Factors
The leading risk factor for SCLC is tobacco use. Up to 98% of people diagnosed with SCLC are current or former smokers. Other contributing factors include:
• Exposure to secondhand smoke
• Contact with radon gas or asbestos
• A personal or family history of lung cancer
• Prior radiation therapy to the chest
• Exposure to certain industrial chemicals
🧪 Diagnosis and Staging
If SCLC is suspected, doctors may use:
• Chest X-rays or CT scans
• PET scans or MRIs to detect spread
• Bronchoscopy or biopsy (to collect a tissue sample)
• Blood tests
• Bone or brain imaging in advanced cases
Staging helps guide the treatment plan and estimate prognosis.
🏥 Treatment Options
Treatment for small cell lung cancer typically involves:
• Chemotherapy – Main treatment, often combined with other methods
• Radiation therapy – Especially for limited-stage disease or brain metastases
• Immunotherapy – Sometimes used with chemo in extensive-stage SCLC
• Clinical trials – Offer access to emerging treatments
• Palliative care – To manage symptoms and improve comfort
Due to the aggressive nature of SCLC, treatment usually begins soon after diagnosis. While cure is more likely in early-stage disease, later stages focus on slowing progression and improving quality of life.