Did you know that lymphoma can develop without warning and doctors might not tell you everything about it? In this article, you reveal the hidden truths about lymphomaโits symptoms, risk factors, treatment options, and the latest medications you need to know to stay ahead.
๐ดWhat Is Lymphoma?
Lymphoma is a type of cancer that affects the lymphatic system, which is part of the bodyโs immune system. This disease involves the abnormal growth of lymphocytes, a type of white blood cell. Lymphoma can occur in different parts of the body, including the lymph nodes, spleen, and bone marrow. Understanding lymphoma is essential for recognizing symptoms, knowing treatment options, and supporting loved ones who may be affected by this illness.
There are two main types of lymphoma: Hodgkin lymphoma and non-Hodgkin lymphoma. Each type behaves differently and requires different treatment approaches.
๐ดTypes of Lymphoma
There are two primary categories of lymphoma:
๐บ๐๐ผ๐ฑ๐ด๐ธ๐ถ๐ป ๐๐๐บ๐ฝ๐ต๐ผ๐บ๐ฎ
This type of lymphoma is less common and mainly affects younger adults. It usually begins in a lymph node and spreads to other parts of the body. The key feature of Hodgkin lymphoma is the presence of Reed-Sternberg cells, a type of abnormal cell found in the lymph nodes.
๐บ๐ก๐ผ๐ป-๐๐ผ๐ฑ๐ด๐ธ๐ถ๐ป ๐๐๐บ๐ฝ๐ต๐ผ๐บ๐ฎ
Non-Hodgkin lymphoma is more common and can occur at any age. It involves several different subtypes, and its behavior can vary greatly. Some subtypes of non-Hodgkin lymphoma grow slowly, while others spread quickly.
Both types can be serious, but advances in treatment have improved survival rates for many people.
๐ดEarly Signs and Symptoms of Lymphoma + Self-Check Guide
The symptoms of lymphoma can vary, depending on the type and where it occurs in the body. Some common signs include:
๐บ๐ฆ๐๐ผ๐น๐น๐ฒ๐ป ๐น๐๐บ๐ฝ๐ต ๐ป๐ผ๐ฑ๐ฒ๐, ๐ผ๐ณ๐๐ฒ๐ป ๐ถ๐ป ๐๐ต๐ฒ ๐ป๐ฒ๐ฐ๐ธ, ๐๐ป๐ฑ๐ฒ๐ฟ๐ฎ๐ฟ๐บ๐ ๐ผ๐ฟ ๐ด๐ฟ๐ผ๐ถ๐ป
๐บ๐จ๐ป๐ฒ๐ ๐ฝ๐น๐ฎ๐ถ๐ป๐ฒ๐ฑ ๐๐ฒ๐ถ๐ด๐ต๐ ๐น๐ผ๐๐
๐บ๐๐ฒ๐๐ฒ๐ฟ ๐ฎ๐ป๐ฑ ๐ฐ๐ต๐ถ๐น๐น๐
๐บ๐ก๐ถ๐ด๐ต๐ ๐๐๐ฒ๐ฎ๐๐
๐บ๐๐ฎ๐๐ถ๐ด๐๐ฒ
๐บ๐๐๐ฐ๐ต๐ ๐๐ธ๐ถ๐ป
๐บ๐ฆ๐ต๐ผ๐ฟ๐๐ป๐ฒ๐๐ ๐ผ๐ณ ๐ฏ๐ฟ๐ฒ๐ฎ๐๐ต ๐ผ๐ฟ ๐ฐ๐ผ๐๐ด๐ต (if lymphoma affects the chest area)
However, these symptoms can also be caused by other conditions, so itโs important to see a doctor for a proper diagnosis if they persist.
๐๐ผ๐ ๐๐ผ ๐๐ต๐ฒ๐ฐ๐ธ ๐๐๐บ๐ฝ๐ต ๐ก๐ผ๐ฑ๐ฒ๐ ๐ถ๐ป ๐๐ต๐ฒ ๐๐ฒ๐ฎ๐ฑ ๐ฎ๐ป๐ฑ ๐ก๐ฒ๐ฐ๐ธ
๐บWith your fingertips, in a gentle circular motion feel the lymph nodes.
๐บStart with the nodes in front of the ear then follow in order finishing just above the collar bone
๐บAlways check your nodes in this order.
๐บCheck both sides for comparison. If you have an enlarged lymph node it may feel like a swelling the size of a pea, sometimes they can be larger.
When feeling the nodes in your neck:
๐บTilt your head towards the side you are examining, this helps to relax the muscle.
๐บNow press your fingers under the muscle.
When checking the lymph nodes above the collar bone:
๐บHunch your shoulders and bring your elbows forward to relax the skin.
๐บNow feel above the collar bone.
How to Check Lymph Nodes in the Armpit:
๐บSit in a comfortable position.
๐บCheck each armpit in turn.
To check the left side, lift your arm slightly then place the fingers of your right hand high into the armpit and then lower your arm.
๐บFeel in the central area of the armpit.
Now move your fingers firmly against the chest wall as follows:
๐บAlong the front border of the armpit.
๐บAlong the back border of the armpit.
๐บFeel along the inner border of the arm.
๐บNow check the other armpit.
How to Check Lymph Nodes in the Groin:
๐บFeel the horizontal chain of nodes in the right groin just below the ligament.
๐บFeel the vertical chain along the upper thigh.
๐บCheck the lymph nodes in the other groin.
๐ดKey Triggers and Risk Factors of Lymphoma
Lymphoma happens when the white blood cells in your lymphatic system change (mutate) into rapidly growing cancer cells that donโt die. Like most cancers, the majority of the genetic mutations that cause lymphoma happen spontaneously, without an identifiable cause. There are several risk factors linked to lymphoma. Some of these increase your chance of developing lymphoma, or particular types of lymphoma. Risk factors for lymphoma include:
๐บ๐๐ด๐ฒ: Lymphoma can develop at any age, but non-Hodgkin lymphoma is more common in older people, while Hodgkin lymphoma is most common in those aged 15โ34 or over 60.
๐บ๐๐ฒ๐ป๐ฑ๐ฒ๐ฟ: Lymphoma is slightly more common in males than females.
๐บ๐๐ฎ๐บ๐ถ๐น๐ ๐๐ถ๐๐๐ผ๐ฟ๐: Having a close relative with lymphoma or another blood cancer slightly increases your risk, due to small inherited genetic changes.
๐บ๐๐ป๐ณ๐ฒ๐ฐ๐๐ถ๐ผ๐ป๐: Certain infections, like EBV, HIV, and HCV, can increase the risk of lymphoma, though most people with these infections do not develop lymphoma.
๐บ๐๐ผ๐๐ฒ๐ฟ๐ฒ๐ฑ ๐๐บ๐บ๐๐ป๐ฒ ๐ฆ๐๐๐๐ฒ๐บ: A weakened immune system, such as from HIV or after an organ transplant, makes it harder to fight infections that may increase lymphoma risk.
๐บ๐๐๐๐ผ๐ถ๐บ๐บ๐๐ป๐ฒ ๐๐ผ๐ป๐ฑ๐ถ๐๐ถ๐ผ๐ป๐: Autoimmune diseases, like Sjรถgrenโs syndrome or rheumatoid arthritis, can increase lymphoma risk due to long-term immune system activation or immune-suppressing medications.
๐บ๐ข๐๐ต๐ฒ๐ฟ ๐๐ผ๐ป๐ฑ๐ถ๐๐ถ๐ผ๐ป๐: Monoclonal Gammopathy of Unknown Significance (MGUS) can sometimes lead to lymphoma, but it is a rare condition.
๐บ๐ฃ๐ฟ๐ฒ๐๐ถ๐ผ๐๐ ๐๐ฎ๐ป๐ฐ๐ฒ๐ฟ ๐ง๐ฟ๐ฒ๐ฎ๐๐บ๐ฒ๐ป๐: Past treatments, like chemotherapy or radiation, may increase the risk of developing lymphoma later on.
๐บ๐ช๐ฒ๐ถ๐ด๐ต๐: Obesity (BMI over 30) is linked to a higher risk of many cancers, including lymphoma.
๐บ๐๐ต๐ฒ๐บ๐ถ๐ฐ๐ฎ๐น๐: Exposure to industrial chemicals, solvents, weedkillers, or old hair dyes may increase the risk of lymphoma, especially in certain occupations.
๐ดMedication and Other Treatment Approaches: What Really Works for Lymphoma
The following drugs have been approved for the treatment of NHL. These medications are used in different treatment regimens, either alone or in combination, to help control lymphoma and improve patient outcomes:
๐บ๐ฅ๐ถ๐๐๐ ๐ฎ๐ป
๐บ๐๐บ๐ฏ๐ฟ๐๐๐ถ๐ฐ๐ฎ
๐บ๐๐ฎ๐น๐พ๐๐ฒ๐ป๐ฐ๐ฒ
๐บ๐๐ฟ๐๐ธ๐ถ๐ป๐๐ฎ
๐บ๐ฉ๐ฒ๐ป๐ฐ๐น๐ฒ๐ ๐๐ฎ
๐บ๐ฅ๐ฒ๐๐น๐ถ๐บ๐ถ๐ฑ
๐บ๐ง๐ฎ๐๐๐ฒ๐ฟ๐ถ๐ธ
๐บ๐ซ๐ฝ๐ผ๐๐ถ๐ผ
๐บ๐ฉ๐ฒ๐น๐ฐ๐ฎ๐ฑ๐ฒ
Treatments vary based on lymphoma type. For example, if you have a slow-growing lymphoma, your healthcare provider may recommend active surveillance (watchful waiting) before starting treatment. In active surveillance, providers carefully monitor your overall health and signs of lymphoma. Common lymphoma treatments include:
๐บ๐๐ต๐ฒ๐บ๐ผ๐๐ต๐ฒ๐ฟ๐ฎ๐ฝ๐
๐บ๐ฅ๐ฎ๐ฑ๐ถ๐ฎ๐๐ถ๐ผ๐ป ๐๐ต๐ฒ๐ฟ๐ฎ๐ฝ๐
๐บ๐ง๐ฎ๐ฟ๐ด๐ฒ๐๐ฒ๐ฑ ๐๐ต๐ฒ๐ฟ๐ฎ๐ฝ๐
๐บ๐๐บ๐บ๐๐ป๐ผ๐๐ต๐ฒ๐ฟ๐ฎ๐ฝ๐
๐บ๐๐๐ฅ ๐ง-๐ฐ๐ฒ๐น๐น ๐๐ต๐ฒ๐ฟ๐ฎ๐ฝ๐
๐บ๐ฆ๐๐ฒ๐บ ๐ฐ๐ฒ๐น๐น (๐ฏ๐ผ๐ป๐ฒ ๐บ๐ฎ๐ฟ๐ฟ๐ผ๐) ๐๐ฟ๐ฎ๐ป๐๐ฝ๐น๐ฎ๐ป๐๐ฎ๐๐ถ๐ผ๐ป
๐ดLymphoma Survival Rates: What Are the Chances of Survival and Death?
Overall, survival rate data show 89% of people with Hodgkin lymphoma and 74% of people with non-Hodgkin lymphoma were alive five years after diagnosis.
Survival rates are estimates based on the experiences of groups of people with the same disease. Survival rate estimates canโt predict how long a person may live with lymphoma. If you have questions about lymphoma survival rates, ask your healthcare provider to explain what you can expect.
AI-Assisted Content Disclaimer
This article was created with AI assistance and reviewed by a human for accuracy and clarity.