Did you know that lymphoma can develop without warning and doctors might not tell you everything about it? In this article, you reveal the hidden truths about lymphomaโ€”its symptoms, risk factors, treatment options, and the latest medications you need to know to stay ahead.

๐Ÿ”ดWhat Is Lymphoma?

Lymphoma is a type of cancer that affects the lymphatic system, which is part of the bodyโ€™s immune system. This disease involves the abnormal growth of lymphocytes, a type of white blood cell. Lymphoma can occur in different parts of the body, including the lymph nodes, spleen, and bone marrow. Understanding lymphoma is essential for recognizing symptoms, knowing treatment options, and supporting loved ones who may be affected by this illness.

There are two main types of lymphoma: Hodgkin lymphoma and non-Hodgkin lymphoma. Each type behaves differently and requires different treatment approaches.

๐Ÿ”ดTypes of Lymphoma

There are two primary categories of lymphoma:

๐Ÿ”บ๐—›๐—ผ๐—ฑ๐—ด๐—ธ๐—ถ๐—ป ๐—Ÿ๐˜†๐—บ๐—ฝ๐—ต๐—ผ๐—บ๐—ฎ

This type of lymphoma is less common and mainly affects younger adults. It usually begins in a lymph node and spreads to other parts of the body. The key feature of Hodgkin lymphoma is the presence of Reed-Sternberg cells, a type of abnormal cell found in the lymph nodes.

๐Ÿ”บ๐—ก๐—ผ๐—ป-๐—›๐—ผ๐—ฑ๐—ด๐—ธ๐—ถ๐—ป ๐—Ÿ๐˜†๐—บ๐—ฝ๐—ต๐—ผ๐—บ๐—ฎ

Non-Hodgkin lymphoma is more common and can occur at any age. It involves several different subtypes, and its behavior can vary greatly. Some subtypes of non-Hodgkin lymphoma grow slowly, while others spread quickly.

Both types can be serious, but advances in treatment have improved survival rates for many people.

๐Ÿ”ดEarly Signs and Symptoms of Lymphoma + Self-Check Guide

The symptoms of lymphoma can vary, depending on the type and where it occurs in the body. Some common signs include:

๐Ÿ”บ๐—ฆ๐˜„๐—ผ๐—น๐—น๐—ฒ๐—ป ๐—น๐˜†๐—บ๐—ฝ๐—ต ๐—ป๐—ผ๐—ฑ๐—ฒ๐˜€, ๐—ผ๐—ณ๐˜๐—ฒ๐—ป ๐—ถ๐—ป ๐˜๐—ต๐—ฒ ๐—ป๐—ฒ๐—ฐ๐—ธ, ๐˜‚๐—ป๐—ฑ๐—ฒ๐—ฟ๐—ฎ๐—ฟ๐—บ๐˜€ ๐—ผ๐—ฟ ๐—ด๐—ฟ๐—ผ๐—ถ๐—ป

๐Ÿ”บ๐—จ๐—ป๐—ฒ๐˜…๐—ฝ๐—น๐—ฎ๐—ถ๐—ป๐—ฒ๐—ฑ ๐˜„๐—ฒ๐—ถ๐—ด๐—ต๐˜ ๐—น๐—ผ๐˜€๐˜€

๐Ÿ”บ๐—™๐—ฒ๐˜ƒ๐—ฒ๐—ฟ ๐—ฎ๐—ป๐—ฑ ๐—ฐ๐—ต๐—ถ๐—น๐—น๐˜€

๐Ÿ”บ๐—ก๐—ถ๐—ด๐—ต๐˜ ๐˜€๐˜„๐—ฒ๐—ฎ๐˜๐˜€

๐Ÿ”บ๐—™๐—ฎ๐˜๐—ถ๐—ด๐˜‚๐—ฒ

๐Ÿ”บ๐—œ๐˜๐—ฐ๐—ต๐˜† ๐˜€๐—ธ๐—ถ๐—ป

๐Ÿ”บ๐—ฆ๐—ต๐—ผ๐—ฟ๐˜๐—ป๐—ฒ๐˜€๐˜€ ๐—ผ๐—ณ ๐—ฏ๐—ฟ๐—ฒ๐—ฎ๐˜๐—ต ๐—ผ๐—ฟ ๐—ฐ๐—ผ๐˜‚๐—ด๐—ต (if lymphoma affects the chest area)

However, these symptoms can also be caused by other conditions, so itโ€™s important to see a doctor for a proper diagnosis if they persist.

๐—›๐—ผ๐˜„ ๐˜๐—ผ ๐—–๐—ต๐—ฒ๐—ฐ๐—ธ ๐—Ÿ๐˜†๐—บ๐—ฝ๐—ต ๐—ก๐—ผ๐—ฑ๐—ฒ๐˜€ ๐—ถ๐—ป ๐˜๐—ต๐—ฒ ๐—›๐—ฒ๐—ฎ๐—ฑ ๐—ฎ๐—ป๐—ฑ ๐—ก๐—ฒ๐—ฐ๐—ธ

๐Ÿ”บWith your fingertips, in a gentle circular motion feel the lymph nodes.

๐Ÿ”บStart with the nodes in front of the ear then follow in order finishing just above the collar bone

๐Ÿ”บAlways check your nodes in this order.

๐Ÿ”บCheck both sides for comparison. If you have an enlarged lymph node it may feel like a swelling the size of a pea, sometimes they can be larger.

When feeling the nodes in your neck:

๐Ÿ”บTilt your head towards the side you are examining, this helps to relax the muscle.

๐Ÿ”บNow press your fingers under the muscle.

When checking the lymph nodes above the collar bone:

๐Ÿ”บHunch your shoulders and bring your elbows forward to relax the skin.

๐Ÿ”บNow feel above the collar bone.

How to Check Lymph Nodes in the Armpit:

๐Ÿ”บSit in a comfortable position.

๐Ÿ”บCheck each armpit in turn.

To check the left side, lift your arm slightly then place the fingers of your right hand high into the armpit and then lower your arm.

๐Ÿ”บFeel in the central area of the armpit.

Now move your fingers firmly against the chest wall as follows:

๐Ÿ”บAlong the front border of the armpit.

๐Ÿ”บAlong the back border of the armpit.

๐Ÿ”บFeel along the inner border of the arm.

๐Ÿ”บNow check the other armpit.

How to Check Lymph Nodes in the Groin:

๐Ÿ”บFeel the horizontal chain of nodes in the right groin just below the ligament.

๐Ÿ”บFeel the vertical chain along the upper thigh.

๐Ÿ”บCheck the lymph nodes in the other groin.

๐Ÿ”ดKey Triggers and Risk Factors of Lymphoma

Lymphoma happens when the white blood cells in your lymphatic system change (mutate) into rapidly growing cancer cells that donโ€™t die. Like most cancers, the majority of the genetic mutations that cause lymphoma happen spontaneously, without an identifiable cause. There are several risk factors linked to lymphoma. Some of these increase your chance of developing lymphoma, or particular types of lymphoma. Risk factors for lymphoma include:

๐Ÿ”บ๐—”๐—ด๐—ฒ: Lymphoma can develop at any age, but non-Hodgkin lymphoma is more common in older people, while Hodgkin lymphoma is most common in those aged 15โ€“34 or over 60.

๐Ÿ”บ๐—š๐—ฒ๐—ป๐—ฑ๐—ฒ๐—ฟ: Lymphoma is slightly more common in males than females.

๐Ÿ”บ๐—™๐—ฎ๐—บ๐—ถ๐—น๐˜† ๐—›๐—ถ๐˜€๐˜๐—ผ๐—ฟ๐˜†: Having a close relative with lymphoma or another blood cancer slightly increases your risk, due to small inherited genetic changes.

๐Ÿ”บ๐—œ๐—ป๐—ณ๐—ฒ๐—ฐ๐˜๐—ถ๐—ผ๐—ป๐˜€: Certain infections, like EBV, HIV, and HCV, can increase the risk of lymphoma, though most people with these infections do not develop lymphoma.

๐Ÿ”บ๐—Ÿ๐—ผ๐˜„๐—ฒ๐—ฟ๐—ฒ๐—ฑ ๐—œ๐—บ๐—บ๐˜‚๐—ป๐—ฒ ๐—ฆ๐˜†๐˜€๐˜๐—ฒ๐—บ: A weakened immune system, such as from HIV or after an organ transplant, makes it harder to fight infections that may increase lymphoma risk.

๐Ÿ”บ๐—”๐˜‚๐˜๐—ผ๐—ถ๐—บ๐—บ๐˜‚๐—ป๐—ฒ ๐—–๐—ผ๐—ป๐—ฑ๐—ถ๐˜๐—ถ๐—ผ๐—ป๐˜€: Autoimmune diseases, like Sjรถgrenโ€™s syndrome or rheumatoid arthritis, can increase lymphoma risk due to long-term immune system activation or immune-suppressing medications.

๐Ÿ”บ๐—ข๐˜๐—ต๐—ฒ๐—ฟ ๐—–๐—ผ๐—ป๐—ฑ๐—ถ๐˜๐—ถ๐—ผ๐—ป๐˜€: Monoclonal Gammopathy of Unknown Significance (MGUS) can sometimes lead to lymphoma, but it is a rare condition.

๐Ÿ”บ๐—ฃ๐—ฟ๐—ฒ๐˜ƒ๐—ถ๐—ผ๐˜‚๐˜€ ๐—–๐—ฎ๐—ป๐—ฐ๐—ฒ๐—ฟ ๐—ง๐—ฟ๐—ฒ๐—ฎ๐˜๐—บ๐—ฒ๐—ป๐˜: Past treatments, like chemotherapy or radiation, may increase the risk of developing lymphoma later on.

๐Ÿ”บ๐—ช๐—ฒ๐—ถ๐—ด๐—ต๐˜: Obesity (BMI over 30) is linked to a higher risk of many cancers, including lymphoma.

๐Ÿ”บ๐—–๐—ต๐—ฒ๐—บ๐—ถ๐—ฐ๐—ฎ๐—น๐˜€: Exposure to industrial chemicals, solvents, weedkillers, or old hair dyes may increase the risk of lymphoma, especially in certain occupations.

๐Ÿ”ดMedication and Other Treatment Approaches: What Really Works for Lymphoma

The following drugs have been approved for the treatment of NHL. These medications are used in different treatment regimens, either alone or in combination, to help control lymphoma and improve patient outcomes:

๐Ÿ”บ๐—ฅ๐—ถ๐˜๐˜‚๐˜…๐—ฎ๐—ป

๐Ÿ”บ๐—œ๐—บ๐—ฏ๐—ฟ๐˜‚๐˜ƒ๐—ถ๐—ฐ๐—ฎ

๐Ÿ”บ๐—–๐—ฎ๐—น๐—พ๐˜‚๐—ฒ๐—ป๐—ฐ๐—ฒ

๐Ÿ”บ๐—•๐—ฟ๐˜‚๐—ธ๐—ถ๐—ป๐˜€๐—ฎ

๐Ÿ”บ๐—ฉ๐—ฒ๐—ป๐—ฐ๐—น๐—ฒ๐˜…๐˜๐—ฎ

๐Ÿ”บ๐—ฅ๐—ฒ๐˜ƒ๐—น๐—ถ๐—บ๐—ถ๐—ฑ

๐Ÿ”บ๐—ง๐—ฎ๐˜‡๐˜ƒ๐—ฒ๐—ฟ๐—ถ๐—ธ

๐Ÿ”บ๐—ซ๐—ฝ๐—ผ๐˜ƒ๐—ถ๐—ผ

๐Ÿ”บ๐—ฉ๐—ฒ๐—น๐—ฐ๐—ฎ๐—ฑ๐—ฒ

Treatments vary based on lymphoma type. For example, if you have a slow-growing lymphoma, your healthcare provider may recommend active surveillance (watchful waiting) before starting treatment. In active surveillance, providers carefully monitor your overall health and signs of lymphoma. Common lymphoma treatments include:

๐Ÿ”บ๐—–๐—ต๐—ฒ๐—บ๐—ผ๐˜๐—ต๐—ฒ๐—ฟ๐—ฎ๐—ฝ๐˜†

๐Ÿ”บ๐—ฅ๐—ฎ๐—ฑ๐—ถ๐—ฎ๐˜๐—ถ๐—ผ๐—ป ๐˜๐—ต๐—ฒ๐—ฟ๐—ฎ๐—ฝ๐˜†

๐Ÿ”บ๐—ง๐—ฎ๐—ฟ๐—ด๐—ฒ๐˜๐—ฒ๐—ฑ ๐˜๐—ต๐—ฒ๐—ฟ๐—ฎ๐—ฝ๐˜†

๐Ÿ”บ๐—œ๐—บ๐—บ๐˜‚๐—ป๐—ผ๐˜๐—ต๐—ฒ๐—ฟ๐—ฎ๐—ฝ๐˜†

๐Ÿ”บ๐—–๐—”๐—ฅ ๐—ง-๐—ฐ๐—ฒ๐—น๐—น ๐˜๐—ต๐—ฒ๐—ฟ๐—ฎ๐—ฝ๐˜†

๐Ÿ”บ๐—ฆ๐˜๐—ฒ๐—บ ๐—ฐ๐—ฒ๐—น๐—น (๐—ฏ๐—ผ๐—ป๐—ฒ ๐—บ๐—ฎ๐—ฟ๐—ฟ๐—ผ๐˜„) ๐˜๐—ฟ๐—ฎ๐—ป๐˜€๐—ฝ๐—น๐—ฎ๐—ป๐˜๐—ฎ๐˜๐—ถ๐—ผ๐—ป

๐Ÿ”ดLymphoma Survival Rates: What Are the Chances of Survival and Death?

Overall, survival rate data show 89% of people with Hodgkin lymphoma and 74% of people with non-Hodgkin lymphoma were alive five years after diagnosis.

Survival rates are estimates based on the experiences of groups of people with the same disease. Survival rate estimates canโ€™t predict how long a person may live with lymphoma. If you have questions about lymphoma survival rates, ask your healthcare provider to explain what you can expect.

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AI-Assisted Content Disclaimer

This article was created with AI assistance and reviewed by a human for accuracy and clarity.